Cosmetic Safety Testing

At Orivida Research, we help cosmetic and personal care brands substantiate product safety and tolerance claims through human clinical testing. From skin irritation and sensitization studies to dermatologist-supervised and ophthalmologist-supervised evaluations, our testing services provide scientific evidence to support product development, safety assessments, and marketing claims.

Human Repeat Insult Patch Test (HRIPT

Human Repeat Insult Patch (Testing) is widely used in the cosmetic industry to evaluate the irritation and sensitization potential of finished formulations. Through repeated product application and a subsequent challenge phase, HRIPT provides valuable information about how the skin responds to a product.

HRIPT results can support claims such as:

  • Dermatologist-tested

  • Non-irritating

  • Non-sensitizing

  • Clinically tested

  • Safe for Sensitive skin

Primary Irritation Testing (PI)

Primary Irritation Testing helps cosmetic brands assess the potential of their products to cause irritation following a single application. The study evaluates visible skin reactions, including redness and other signs of irritation, under controlled conditions.

Depending on the study results, PI testing can support claims such as:

  • Dermatologist-tested

  • Clinically tested

  • Non-irritating

Safety-In-Use Testing (SIU) with Dermaologist

Our Safety-in-Use studies evaluate cosmetic products under normal or intended conditions of use, with dermatologist oversight and evaluation. These studies help brands understand how their formulations perform on different skin types and provide clinical evidence of product tolerance.

Studies can be designed for the general population or specific skin types, including sensitive, acne-prone, rosacea-prone, and eczema-prone skin.

Depending on the study design and results, SIU testing can support claims such as:

  • Dermatologist Tested

  • Safe for Sensitive Skin

  • Clinically Tested

  • Safe for Acne-Prone skin

  • Safe for Rosacea-Prone Skin

  • Safe for Eczema-Prone skin

Ophthalmological Safety Testing

Our ophthalmological safety studies evaluate cosmetic products intended for use around the eyes, including mascaras, eyeliners, eye creams, and makeup removers. Studies are conducted with an ophthalmologist to assess ocular tolerance and potential irritation during intended product use.

Depending on the study design and results, testing can support claims such as;

  • Ophthalmologist Tested

  • Safe for sensitive eyes

  • Safe for contact wearers

  • Non-Irritating to the eye area