🧴 Safety In Use Studies: Real-World Product Safety Backed by Clinical Observation
When it comes to skincare, haircare, and personal care products, safety isn’t just a claim — it’s a commitment. One of the most effective ways to ensure your product lives up to that commitment is through a Safety In Use (SIU) study.
âś… What Is a Safety In Use Study?
A Safety In Use (SIU) study is a type of human observational trial that evaluates how a product performs during normal, everyday use. Volunteers use the product as instructed — typically over 15 to 30 days — and are monitored for any signs of irritation, sensitivity, or discomfort.
Key objectives include:
Confirming the product is well-tolerated
Detecting any adverse skin reactions
Supporting “dermatologist tested” or “clinically tested for safety” claims
đź©ş Dermatologist Oversight Adds Credibility
At Orivida Research, SIU studies are conducted with oversight from board-certified dermatologists. This allows brands to back up safety-related claims with real data — and real credibility.
Common supported claims include:
Dermatologist tested
Clinically shown to be non-irritating
Safe for sensitive skin
Tolerated in everyday use
🔬 SIU vs. Patch Testing (HRIPT): What’s the Difference?
It’s easy to confuse SIU studies with HRIPT (Human Repeat Insult Patch Testing) — but they serve different purposes:
SIU Study
Real-world product usage
Observational, over 2 weeks to a month
Evaluates tolerance in normal
Supports tolerability claims
HRIPT
Controlled lab patch testing
Repeated exposure to check for sensitization
Detects irritation or allergic potential
Supports claims for non-irritating and hypoallergenic labeling
SIU = real-world data. HRIPT = sensitization risk control.
Both matter, depending on your goals.
🧪 Why Brands Choose SIU Studies
Safety In Use studies are especially valuable for:
Leave-on products (e.g., moisturizers, sunscreens)
Haircare and scalp treatments
Products intended for sensitive or acne-prone skin
“Free from irritation” or “gentle enough for daily use” claims
đź”— Our Approach at Orivida Research
We work closely with brands to design custom SIU protocols aligned with your formulation, target demographic, and market claims. Our panels are diverse, and our standards are high — because safety isn’t a checkbox. It’s the beginning of brand trust.
📩 Have a product you’d like to test?
Reach out to us at Hello@orivida-research.com to learn how we can support your next clinical study.
Orivida Research — Clinical Testing That Builds Confidence
#SafetyInUse #ClinicalTesting #SkincareScience #DermatologistTested #HRIPTvsSIU #ProductSafety #OrividaResearch